ABSTRACT
La úlcera genital aguda (UGA) o úlcera de Lipschütz constituye una infrecuente entidad clínica caracterizada por la aparición de úlceras genitales en niñas y adolescentes que no han iniciado su actividad sexual. El cuadro es de inicio agudo, con formación de úlceras dolorosas habitualmente precedidas en su aparición por manifestaciones sistémicas tales como fiebre, cefalea, astenia, adinamia, mialgias y adenopatías inguinales, y donde el estudio microbiológico de la lesión descarta un posible origen infeccioso. A pesar de presentar un cuadro clínico característico, esta enfermedad constituye una entidad poco conocida y por tanto subdiagnosticada, motivo por el cual presentamos el caso de una paciente de 10 años con diagnóstico de UGA realizado en el Departamento de Dermatología de la Pontificia Universidad Católica de Chile.
Acute genital ulcer (AGU) or Lipschütz ulcer is a rare clinical entity characterized by the appearance of genital ulcers in children and adolescents who have not initiated sexual activity. The picture is of acute onset, with formation of painful ulcers on their occurrence usually preceded by systemic manifestations such as fever, headache, fatigue, weakness, muscle pain and inguinal lymphadenopathy, and where the microbiological study of injury rule out a possible infectious origin. Despite presenting a characteristic clinical picture, this disease is a little known entity and under diagnosed, we present the case of a 10 years old girl diagnosed with UGA conducted at the Department of Dermatology, Catholic University of Chile.
Subject(s)
Humans , Female , Child , Vulvar Diseases/diagnosis , Ulcer/diagnosis , Acute DiseaseABSTRACT
Background: We report a 74 years old male consulting for multiple painless non pruriginous pink plaques and nodules of truncal distribution that appeared 15 days earlier. A skin biopsy disclosed a blastic plasmocytoid dendritic cell neoplasm. A staging CAT scan showed lymphadenopathies located around the trachea and its bifurcation. A bone marrow biopsy did not show tumor infiltration. The patient has been treated with four cycles of cyclophosphamide-doxorubicin-vincristine-prednisone, obtaining a partial remission of the lesions.
Subject(s)
Aged , Humans , Male , Dendritic Cells/pathology , Hematologic Neoplasms/pathology , Skin Neoplasms/pathology , Antigens, CD/analysis , Immunohistochemistry , Tomography, X-Ray ComputedABSTRACT
Se presenta el caso de una mujer de 32 años, quien consultó por presentar desde hace 6 meses nódulos múltiples y pruriginosos en ambos labios mayores, prurito que se exacerbaba durante la menstruación. El estudio anatomo-patológico demostró una proliferación dérmica de conductos pequeños revestidos por una doble capa de células cuboídeas normotípicas, y rodeados por un estroma fibroso compatibes con un siringoma...
We report a case of a 32 year-old woman, who consulted to present for 6 months and multiple and itchy nodules in both labia majora, itching that was exacerbated during menstruation. The pathological study showed a dermal proliferation of small ducts lined by a double layer of normotipic cuboidal cells, and surrounded by a fibrous stroma compatibes a syringoma...
Subject(s)
Humans , Adult , Female , Vulvar Neoplasms/pathology , Sweat Gland Neoplasms/pathology , Syringoma/pathologyABSTRACT
Pseudolinfoma cutáneo es el término utilizado para indicar un grupo de trastornos linfoproliferativos benignos de la piel, siendo el linfocitoma cutis una forma de seudolinfoma de células B. Clínicamente se manifiesta como nódulos o placas solitarias, generalmente localizados en la cara de mujeres jóvenes. Su etiopatogenia estaría relacionada con una respuesta inmunológica local exagerada ante diversos desencadenantes tales como, picadura de insectos, acupuntura, vacunas, tatuajes, medicamentos e infecciones. Se presentan dos casos de pacientes con diagnóstico de linfocitoma cutis realizado en la Unidad de Anatomía Patológica del Hospital Hernán Henríquez de Temuco.
Cutaneous pseudolymphoma is the term used to indicate a group of benign lymphoproliferative disorders of the skin, being the cutaneous lymphomas a form of B-cell pseudolymphoma. Clinically it manifests as solitary nodules or plaques, usually located on the face of young women. Its pathogenesis could be related to an exaggerated local immune response to various causes such as insect bites, acupuncture, vaccinations, tattoos, drugs and infections. We present two cases of patients diagnosed with skin linfocitoma made in the Pathology Unit in Hernán Henríquez Hospital of Temuco.
Subject(s)
Aged , Pseudolymphoma/diagnosis , Pseudolymphoma/therapy , Skin Diseases/diagnosis , Skin Diseases/therapy , Castleman Disease/diagnosis , Castleman Disease/therapyABSTRACT
We report a 54-year-old male that, after working in a rural zone of Rio de Janeiro, Brazil, presented with an itching cutaneous lesion in the wrist with a black small central zone. The patient extracted from the lesion a on of 0.5 mm diameter. The pathological study of the insect recognized its body segments. The epidemiological background and the characteristics of the lesion led to the diagnosis of tungiasis.